解剖学和形态学
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听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
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内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
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医学,全科和内科
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神经系统科学
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产科医学和妇科医学
肿瘤学
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整形外科学
耳鼻喉科学
病理学
儿科学
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药理学和药剂学
生理学
基本医疗保健
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放射学,核医学和医学成像
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abstract::Retapamulin is a semisynthetic pleuromutilin compound with in vitroactivity against Gram-positive bacteria, no cross-resistance to other classes of antimicrobial agents in current use and a low potential for development of resistance. A 1% ointment formulation has been developed for clinical use, and a placebo-control...
journal_title:Future microbiology
pub_type: 临床试验,杂志文章
doi:10.2217/17460913.2.6.591
更新日期:2007-12-01 00:00:00
abstract::The past decade has seen a significant increase in the incidence of invasive fungal infections. The antifungal armamentarium for the treatment of serious fungal infections remains limited. A possible approach to overcoming antifungal drug resistance and high mortality rates seen in severe fungal infections is to combi...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.2.2.115
更新日期:2007-04-01 00:00:00
abstract::Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.1.4.387
更新日期:2006-12-01 00:00:00
abstract::Community-acquired pneumonia remains an important cause of disease and death both in the developed and the developing worlds, despite the ready availability of potent antimicrobial agents to which the organisms remain susceptible. Furthermore, disease management is complicated by emerging resistance of the common path...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.1.3.271
更新日期:2006-10-01 00:00:00
abstract::Micafungin is a new drug in the echinocandin class and is currently being investigated in Phase III clinical trials. Like other echinocandins, it inhibits 1,3-beta-D-glucan synthesis, thus achieving fungicidal activity against virtually all Candida spp., including those resistant to fluconazole, and fungistatic activi...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.1.2.161
更新日期:2006-08-01 00:00:00
abstract::Folate metabolism of the malaria parasites provides two targets for current antimalarials: dihydrofolate reductase and dihydropteroate synthase. Dihydrofolate reductase inhibitors have been used as antimalarials over the past few decades, often in combination with dihydropteroate synthase inhibitors. Resistance to the...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.1.1.113
更新日期:2006-06-01 00:00:00